PEPTOSYL is a first-line defence against digestive disturbances in horses and dogs, with a wide safety margin, and analgesic, antiseptic and antacid actions.


  • PEPTOSYL is a first-line defence against diarrhoea and digestive disturbances in horses, foals and dogs.
  • PEPTOSYL is Bismuth salicylate oral suspension.
  • Non-antibiotic treatment for non-infectious & dietary diarrhoea.
  • PEPTOSYL has gut protective, antacid, antiseptic properties, and is anti-inflammatory to control pain.

Bentonite is a natural clay earth material with properties similar to activated charcoal. It has the ability to bind (and neutralise) bacterial endotoxins. Bismuth salicylate is converted to Bismuth carbonate and Sodium salicylate after administration. Bismuth lines and protects the mucosal (gut lining) surface of the stomach and intestines, absorbs toxic compounds such as endotoxins and has protective, antacid and antiseptic properties. The salicylate component is anti-inflammatory, and rapidly reduces the pain associated with gut inflammation and disturbances. The majority of canine and equine gastrointestinal disturbances are not of bacterial origin. Therefore, PEPTOSYL is a safe, non-complicating treatment in most foals, puppies, and adult horses and dogs with digestive upsets of nutritional or non-bacterial origin. Most canine and equine gut disturbances relate to incorrect management or diet, nutrition, or stress, rather than infection.

PEPTOSYL is indicated for the control and treatment of diarrhoea and pain associated with non-bacterial gastrointestinal disturbance such as enteritis, gastritis, and colitis. Being non-antibiotic, PEPTOSYL does not contribute to bacterial resistance. Oral bismuth preparations are well researched in both humans and animals and are reported to be free of toxic side effects.


PEPTOSYL has no application in the training of normal, healthy horses and dogs, but can be used where indicated in cases of gastrointestinal disturbance. It will not “mask” any serious veterinary problems, but will rapidly relieve the majority of gut upsets from dietary or non-infectious causes. If rapid response is not seen, seek a veterinary diagnosis of the condition without delay.


Administer orally.
Horses: 0.5 – 1.0 mL per kg
Dogs: 0.25 – 0.5 mL per kg

Repeat dose every 6 hours for 36 hours. Thence at 12 hour intervals for a further 2 to 3 days.

Where possible, withhold food for 24 hours (but do not restrict nursing in foals or puppies).

Do not administer for prolonged periods to animals less than 30 days old.


Bismuth sub-salicylate 17.5 mg/mL

Weight 0.230 kg


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